Yong Gu (Ph.D.)

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Ph.D. in Speech Signal Processing, 1989, Swansea University , Swansea, UK

B.Sc. in Computer Science, 1982. Fudan University , Shanghai, China

High school graduation, 1978. Songjiang Erzhong, 松江二中, Shanghai, China



2004-now: The Sanger Institute, Cambridge, UK 

1992-2004: Algorithm Development Manager (Scientist before 1995), Speech System Devision, Logica Plc. (late spin-off Vocalis Plc), Cambridge, UK

1989-1992: Post-doctoral Research associate, in Department of Computer Science, King's College, University of London, London, UK

1982-1985: Associate lecturer, Department of Computer Science, Wuhan University, Wuhan, China


Selected Publications:

Shi W, Massaia A, Louzada S, Banerjee R, Hallast P, Chen Y, Bergström A, Gu Y, Leonard S, Quail MA, Ayub Q, Yang F, Tyler-Smith C, Xue Y "Copy number variation arising from gene conversion on the human Y chromosome", Human Genetics 2017 Dec 5. doi: 10.1007/s00439-017-1857-9

Louise Aigrain, Yong Gu, Michael A. Quail "Quantitation of next generation sequencing library preparation protocol efficiencies using droplet digital PCR assays - a systematic comparison of DNA library preparation kits for Illumina sequencing", BMC Genomics, June 2016

Samuel O Oyola, Magnus Manske, Susana Camino, Antoine Claessens, William L Hamilton, Mihir Kekre, Eleanor Drury, Daniel Mead, Yong Gu, Alistair Miles, Bronwyn MacInnis, Chris Newbold, Mattew Berriman, Dominic P Kwiatkowski "Optimized Whole-Genome Amplification Strategy for Extremely AT-Biased Template", DNA research: 09/2014

Michael A Quail, Miriam Smith, David Jackson, Steven Leonard, Thomas Skelly, Harold P Swerdlow, Yong Gu and Peter Ellis "SASI-Seq: sample assurance Spike-Ins, and highly differentiating 384 barcoding for Illumina sequencing" BMC Genomics, 15:100 Febuary 2014

Naomi Park, Lesley Shirley, Yong Gu, Thomas M. Keane, Harold Swerdlow and Michael A. Quail "An improved approach to mate-paired library preparation for Illumina sequencing", Methods in Next Generation Sequencing. Volume 1, Pages 10-20, ISSN (Online) 2084-7173, DOI: 10.2478/mngs-2013-0001, July 2013

Kerstin Howe, ..., Yong Gu, ..., Derek L. Stemple, "The zebrafish reference genome sequence and its relationship to the human genome", Nature 496, 498–503, 25 April 2013

Samuel O. Oyola, Yong Gu, Magnus Manske, Thomas D. Otto, John O'Brien, Daniel Alcock, Bronwyn MacInnis, Matthew Berriman, Chris I. Newbold, Dominic P. Kwiatkowski, Harold P. Swerdlow, and Michael A. Quail, "Efficient Depletion of Host DNA Contamination in Malaria Clinical Sequencing", J Clin Microbiol. 2013 March; 51(3): 745–751.

Aylwyn Scally, …, Yong Gu, …, Richard Durbin, “Insights into hominid evolution from the gorilla genome sequence”, Nature 483, 169–175, March 2012

Michael Quail, Miriam E Smith, Paul Coupland, Thomas D Otto, Simon R Harris, Thomas R Connor, Anna Bertoni, Harold P Swerdlow and Yong Gu, "A tale of three next generation sequencing platforms: Comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq Sequencers", Journal: BMC Genomics 2012, 13:341

Elizabeth P. Murchison, …, Yong Gu, …, Michael R. Stratton, “Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer”, Cell, Volume 148, Issue 4, 780-791, February 2012

Michael A Quail, Thomas D Otto, Yong Gu, Simon R Harris, Thomas F Skelly, Jacqueline A McQuillan, Harold P Swerdlow and Samuel O Oyola, “Investigation of the optimal enzyme for amplification during NGS library preparation”, Nature Methods, Volume: 9, 2012

Samuel O Oyola, Thomas D Otto, Yong Gu, Gareth Maslen, Magnus Manske, Susana Campino, Daniel J Turner, Bronwyn Maclnnis, Dominic P Kwiatkowski, Harold P Swerdlow and Michael A Quail,  “Optimizing Illumina Next-Generation Sequencing library preparation For extremely AT-biased genomes”  BMC Genomics 2012, 13:1

Berriman M, …, Gu Y, …, El-Sayed NM, “The genome of the blood fluke Schistosoma mansoni.” Nature 2009;460;7253;352-8 PUBMED: 19606141; PMC: 2756445; DOI: 10.1038/nature08160

Gu, Y., and Thomas, T. "A Text-Independent Speaker Verification System Using Support Vector Machines Classifier", in Eurospeech-2001, September 2001

Tan, B. T., Gu, Y., and Thomas, T. "Word Level Confidence Measures Using N-Best Sub-Hypotheses Likelihood Ratio", in Eurospeech-2001, September 2001

Gu, Y. Jongebloed H., Iskra D., Els den Os and Boves L. "Speaker Verification in Operational environments-- monitoring for improved service operation", in Proc. ICSLP, October, 2000.

Gu, Y., and Thomas, T. "Advances on HMM-based Text-dependent Speaker Verification" in Proc. ICSLP, October, 2000.

Gu, Y., and Thomas, T. "Competition-based score analysis for utterance verificationin name recognition," in Proc. ICSLP, October, 2000.

Tan, B. T., Gu, Y., and Thomas, T. "Utterance verification based speech recognition system," in Proc. ICSLP, October, 2000.

Gu Y. and Thomas T., "A Competition-based Score Measurement for Speaker Verification", EUSIPCO 2000.

Tan, B. T., Gu, Y., and Thomas, T. "Word Confusability Measures for Vocabulary Selection in Speech Recognition," in Proc. IEEE Workshop on Automtic Speech Recognition and Understanding (ASRU), Colordo, USA, December, 1999.

Gu Y. and T. Thomas "A Hybrid Score Measurement for HMM-Based Speaker Verification", ICASSP'99, Phineox Arizona USA, March 1999.

Gu Y. and Thomas T., "An Implementation and Evaluation of an On-line Speaker Verification System for Field Trial", in ICSLP-98

Tan B. T., Gu Y. and Thomas T., "Evaluation and Implementation of A Voice-Activated Dialing System with Utterance Verification", in ICSLP-98

Tan B. T., Gu Y. and Thomas T. "Implementation and Evaluation of A Voice-Activated Dialling System", IVTTA'98, Italy, 1998

Gu Y. and Mason J., "Speaker Normalisation via a Linear Transformation on a Perceptual Feature Space and its Benefits in ASR", Eurospeech'89, Paris France, September 1989.

Mason J., Gu Y. and Goatcher J, "Adaptation in Speech Recognition", 1988 Alvey Technical Conference, U.K.

Gu Y. and Mason J., "A Speaker-Correlation Weighted RPS Distance Measure for Speech Recognition", IEEE Symposium on Information Theory, Japan, 1988.

Mason J. and Gu Y., "Perceptually-based Feature in ASR", IEE Colloquium of Speech Processing, U.K. 1988.

Gu Y. and Mason J., "A Comparison Between Vocal Tract and Auditory Feature Analysis in ASR System", Eurospeech'87 Edinburgh, U.K., 1987.








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